Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.54 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | F7 | P08709 | 3/20 | 0.46 |
| ▸ | F3 | P13726 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | FABP3 | P05413 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24627656 | 1.00 | MGLL (0.55) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL24627584 | 1.00 | MGLL (0.55) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL24627505 | 0.98 | MGLL (0.55) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL24627685 | 0.95 | MGLL (0.59) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL24627568 | 0.94 | MGLL (0.56) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL25801068 | 0.94 | DNM1 (0.55) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL25076629 | 0.93 | MGLL (0.56) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL24627812 | 0.93 | MGLL (0.56) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL25076710 | 0.93 | MGLL (0.55) | MGLLALDH1A1MAPTTHRBCNR1 | |
| SCHEMBL24627526 | 0.92 | MGLL (0.57) | MGLLALDH1A1MAPTTHRBCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220218622-A1 | IONIZABLE LIPIDS AND METHODS OF MANUFACTURE AND USE THEREOF | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2022-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220218622-A1 | IONIZABLE LIPIDS AND METHODS OF MANUFACTURE AND USE THEREOF | NPC1L1, PLA2G4A, PLA2G2A | MGLL 429/4885ALDH1A1 3237/4885MAPT 2748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.