Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.38 |
| ▸ | LIPC | P11150 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL14735926 | 0.98 | ABCB11 (0.52) | ABCB11P2RX7SIGMAR1LIPGLIPC | |
| SCHEMBL6485285 | 0.86 | P2RX7 (0.53) | P2RX7LIPGLIPCMEN1KMT2A | |
| SCHEMBL4116624 | 0.83 | P2RX7 (0.64) | P2RX7LIPGLIPCMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5924089 | 0.82 | P2RX7 (0.64) | P2RX7LIPGLIPCMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5960230 | 0.82 | P2RX7 (0.64) | P2RX7LIPGLIPCMEN1KMT2A | |
| SCHEMBL5333690 | 0.82 | P2RX7 (0.52) | P2RX7LIPGLIPCMEN1KMT2A | |
| SCHEMBL6052984 | 0.80 | ABCB11 (0.64) | ABCB11P2RX7 | |
| SCHEMBL4129968 | 0.80 | ABCB11 (0.81) | ABCB11P2RX7 | |
| SCHEMBL4129964 | 0.80 | ABCB11 (0.81) | ABCB11P2RX7 | |
| SCHEMBL5142841 | 0.79 | NPC1 (0.44) | P2RX7MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2542670-A2 | INDUCED DENDRITIC CELL COMPOSITIONS AND USES THEREOF | President and Fellows of Harvard College (US) | 2013-01-09 | — | — | EP | disclosed |
| WO-2011109833-A2 | INDUCED DENDRITIC CELL COMPOSITIONS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-09-09 | — | — | WO | disclosed |