Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | TP53 | P04637 | 2/20 | 0.66 |
| ▸ | ESRRG | P62508 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.65 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.65 |
| ▸ | RELA | Q04206 | 1/20 | 0.65 |
| ▸ | KCNK3 | O14649 | 7/20 | 0.62 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | AURKA | O14965 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14363224 | 0.95 | MEN1 (0.73) | MEN1KMT2ARXFP1NPC1RAB9A | |
| SCHEMBL10090678 | 0.89 | KMT2A (0.72) | MEN1KMT2ARXFP1NPC1RAB9A | |
| SCHEMBL24628422 | 0.87 | SAE1 (0.63) | MEN1KMT2ARXFP1NPC1RAB9A | |
| SCHEMBL24628731 | 0.86 | NPC1 (0.71) | MEN1KMT2ANPC1RAB9ATP53 | |
| SCHEMBL259706 | 0.85 | MEN1 (0.77) | MEN1KMT2ARXFP1NPC1RAB9A | |
| SCHEMBL729117 | 0.84 | KCNK3 (0.71) | MEN1KMT2ANPC1RAB9ATP53 | |
| SCHEMBL26832081 | 0.83 | KMT2A (0.59) | MEN1KMT2ANPC1RAB9ATP53 | |
| SCHEMBL8461683 | 0.83 | MEN1 (0.73) | MEN1KMT2ARXFP1NPC1RAB9A | |
| SCHEMBL259468 | 0.82 | KCNK3 (0.87) | MEN1KMT2ARXFP1NPC1RAB9A | |
| SCHEMBL29434800 | 0.82 | KCNK3 (0.87) | MEN1KMT2ARXFP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4276092-A1 | COMPOUND LIBRARY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-15 | — | — | EP | disclosed |
| WO-2022149617-A1 | COMPOUND LIBRARY | 中外製薬株式会社 | 2022-07-14 | — | — | WO | disclosed |