Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 9/20 | 0.45 |
| ▸ | CA12 | O43570 | 9/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2458539 | 0.86 | DYRK1A (0.38) | DYRK1ACA2CA12CYP2A6 | |
| SCHEMBL26260180 | 0.76 | CYP1A2 (0.46) | — | |
| SCHEMBL26260213 | 0.74 | ESR1 (0.41) | — | |
| SCHEMBL2036162 | 0.73 | CA2 (0.60) | DYRK1ACA2CA12CYP2A6ENPP1 | |
| SCHEMBL2464029 | 0.72 | PIK3CA (0.37) | — | |
| SCHEMBL2462872 | 0.72 | DYRK1A (0.54) | DYRK1ACA2CA12CHRNA7KCNH2 | |
| SCHEMBL25061130 | 0.72 | DYRK1A (0.58) | DYRK1ACA2CA12CYP2A6CHRNA7 | |
| SCHEMBL23555362 | 0.72 | CA2 (0.64) | DYRK1ACA2CA12CYP2A6CHRNA7 | |
| SCHEMBL20984002 | 0.72 | DYRK1A (0.58) | DYRK1ACA2CA12CYP2A6CHRNA7 | |
| SCHEMBL15537714 | 0.72 | DYRK1A (0.58) | DYRK1ACA2CA12CYP2A6ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110237633-A1 | SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2011-09-29 | — | — | US | disclosed |
| WO-2010068287-A2 | SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | ANGION BIOMEDICA CORP. (US) | 2010-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237633-A1 | SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | HGF, HDGF, MET | DYRK1A 4134/4885CA2 4490/4885CA12 3173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.