Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24628143 | 1.00 | CYP2A13 (0.31) | CYP2A13SIGMAR1HSD11B1HTR6 | |
| SCHEMBL24628148 | 0.82 | SIGMAR1 (0.39) | SIGMAR1HTR6 | |
| SCHEMBL6971710 | 0.82 | SIGMAR1 (0.36) | SIGMAR1HTR6 | |
| SCHEMBL21563294 | 0.74 | GNAI3 (0.31) | — | |
| SCHEMBL14386195 | 0.74 | SIGMAR1 (0.35) | SIGMAR1 | |
| SCHEMBL23635339 | 0.71 | ADRB1 (0.30) | — | |
| SCHEMBL17489071 | 0.70 | HTR6 (0.32) | HTR6 | |
| SCHEMBL27496350 | 0.68 | CYP2A13 (0.47) | CYP2A13HSD11B1 | |
| SCHEMBL3998603 | 0.64 | CHRNA7 (0.38) | — | |
| SCHEMBL4484576 | 0.64 | CHRNA7 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022150461-A1 | MODULATORS OF TRPML, THEIR COMPOSITIONS AND METHODS OF USE | CARAWAY THERAPEUTICS, INC. (US) | 2022-07-14 | — | — | WO | disclosed |