SCHEMBL25899100

SCHEMBL25899100

CC(C)c1cnc2nc(N)nc(O)c2n1

nearest known ligand 0.39

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.39
PIK3CG P48736 4/20 0.38
PIK3CA P42336 1/20 0.35
PIK3CB P42338 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
ADORA2A P29274 3/20 0.34
DHFR P00374 4/20 0.34
NOS1 P29475 3/20 0.32
ADORA1 P30542 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4361085 0.86 HSD17B10 (0.48) HSD17B10PIK3CGPIK3CAPIK3CBHDAC6
SCHEMBL25899104 0.83 ADORA2A (0.48) PIK3CGPIK3CAPIK3CBHDAC6ADORA2A
SCHEMBL11628253 0.83 PIK3CG (0.35) HSD17B10PIK3CGPIK3CAPIK3CBHDAC6
SCHEMBL25899163 0.81 HSD17B10 (0.34) HSD17B10
SCHEMBL24629319 0.80 PIK3CG (0.42) PIK3CGPIK3CAPIK3CBHDAC6ADORA2A
SCHEMBL9201051 0.80 HSD17B10 (0.38) HSD17B10PIK3CGPIK3CAPIK3CBHDAC6
SCHEMBL25899167 0.78 HSD17B10 (0.32) HSD17B10
SCHEMBL6239850 0.77 PIK3CG (0.41) PIK3CGPIK3CAPIK3CBHDAC6ADORA2A
SCHEMBL11301495 0.77 HSD17B10 (0.38) HSD17B10PIK3CGPIK3CAPIK3CBHDAC6
Xanthopterin SCHEMBL906220 0.77 PIK3CG (0.46) PIK3CGPIK3CAPIK3CBHDAC6ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230279426-A1 MODIFIED VIRAL COMPOSITIONS FOR VIRAL TRANSDUCTION LYCIA THERAPEUTICS, INC. 2023-09-07 US disclosed
US-20230279426-A1 MODIFIED VIRAL COMPOSITIONS FOR VIRAL TRANSDUCTION LYCIA THERAPEUTICS, INC. 2023-09-07 US disclosed
US-20230226214-A1 BIFUNCTIONAL BRIDGING COMPOSITIONS FOR VIRAL TRANSDUCTION LYCIA THERAPEUTICS, INC. 2023-07-20 US disclosed
US-20230226214-A1 BIFUNCTIONAL BRIDGING COMPOSITIONS FOR VIRAL TRANSDUCTION LYCIA THERAPEUTICS, INC. 2023-07-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230226214-A1 BIFUNCTIONAL BRIDGING COMPOSITIONS FOR VIRAL TRANSDUCTION HAVCR2, FCGR3B, FCGR2A HSD17B10 4659/4885PIK3CG 1942/4885PIK3CA 2942/4885
US-20230279426-A1 MODIFIED VIRAL COMPOSITIONS FOR VIRAL TRANSDUCTION HAVCR2, ASGR1, FCGR3B HSD17B10 4755/4885PIK3CG 1698/4885PIK3CA 2370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.