Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | RAPGEF4 | Q8WZA2 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29769190 | 1.00 | L3MBTL1 (0.49) | L3MBTL1CA1CA2RAPGEF4HTT | |
| SCHEMBL24630039 | 0.89 | L3MBTL1 (0.45) | L3MBTL1CA1CA2RAPGEF4HTT | |
| SCHEMBL21439014 | 0.85 | HTR6 (0.45) | L3MBTL1CA1CA2RAPGEF4HTT | |
| SCHEMBL21438920 | 0.85 | RAPGEF4 (0.47) | L3MBTL1CA1CA2RAPGEF4HTR6 | |
| SCHEMBL15392858 | 0.84 | L3MBTL1 (0.55) | L3MBTL1CA1CA2RAPGEF4HTT | |
| SCHEMBL21439220 | 0.82 | TCF4 (0.44) | L3MBTL1CA1CA2TDP1TSHR | |
| SCHEMBL17518587 | 0.82 | L3MBTL1 (0.49) | L3MBTL1CA1CA2RAPGEF4HTT | |
| SCHEMBL31022931 | 0.80 | L3MBTL1 (0.45) | L3MBTL1CA1CA2RAPGEF4HTT | |
| SCHEMBL30993567 | 0.78 | L3MBTL1 (0.43) | L3MBTL1CA1CA2RAPGEF4HTT | |
| SCHEMBL17504506 | 0.78 | L3MBTL1 (0.48) | L3MBTL1CA1CA2RAPGEF4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023250157-A9 | INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS LIPOAMIDE DEHYDROGENASE | CORNELL UNIVERSITY (US) | 2024-01-25 | — | — | WO | disclosed |
| WO-2023250157-A1 | INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS LIPOAMIDE DEHYDROGENASE | CORNELL UNIVERSITY (US) | 2023-12-28 | — | — | WO | disclosed |
| WO-2022150574-A1 | INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS LIPOAMIDE DEHYDROGENASE | CORNELL UNIVERSITY (US) | 2022-07-14 | — | — | WO | disclosed |