Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2456739 | 0.88 | PPARD (0.56) | PPARDTSHRBTN3A1TP53TDP1 | |
| SCHEMBL2990604 | 0.82 | PPARD (0.54) | PPARDTSHRCA12CA1CA2 | |
| SCHEMBL7268189 | 0.78 | PPARD (0.64) | PPARDTSHRTP53TDP1 | |
| SCHEMBL5017294 | 0.78 | PPARD (0.64) | PPARDTSHRTP53TDP1 | |
| SCHEMBL24475840 | 0.78 | PPARD (0.54) | PPARDTSHRTP53TDP1CA12 | |
| SCHEMBL2383184 | 0.78 | PPARD (0.54) | PPARDTSHRTDP1 | |
| SCHEMBL6839745 | 0.76 | PPARD (0.52) | PPARDTSHRTP53TDP1CA12 | |
| SCHEMBL29169497 | 0.76 | PPARD (0.52) | PPARDTSHRCA12CA1CA2 | |
| SCHEMBL24476440 | 0.76 | PPARD (0.47) | PPARDTSHRCA12CA1CA2 | |
| SCHEMBL11323349 | 0.75 | PPARD (0.61) | PPARDTSHRTP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8017596-B2 | Phosphonates useful as modulators of T-γ-9-δ-2 activity | INNATE PHARMA, S.A. (FR) | 2011-09-13 | — | — | US | disclosed |
| US-8017596-B2 | Phosphonates useful as modulators of T-γ-9-δ-2 activity | INNATE PHARMA, S.A. (FR) | 2011-09-13 | — | — | US | disclosed |
| US-20100204184-A1 | Phosphonates useful as modulators of T-gamma-9-delta-2 activity | LABORATOIRES MAYOLY SPINDLER (FR) | 2010-08-12 | — | — | US | disclosed |
| US-20100204184-A1 | Phosphonates useful as modulators of T-gamma-9-delta-2 activity | LABORATOIRES MAYOLY SPINDLER (FR) | 2010-08-12 | — | — | US | disclosed |
| US-20060241087-A1 | Phosphonates useful as modulators of t $g(g)9$g(d)2 lymphocyte activity | MONTERO JEAN-LOUIS | 2006-10-26 | — | — | US | disclosed |
| US-6902608-B2 | Dental material containing phosphonic acids | ERNST MUHLBAUER GMBH & CO., KG (DE) | 2005-06-07 | — | — | US | disclosed |
| US-20030167968-A1 | Dental material containing phosphonic acids | MÜHLBAUER TECHNOLOGY GMBH (DE) | 2003-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030167968-A1 | Dental material containing phosphonic acids | PHOSPHO1, EPN1, PTK2 | PPARD 1569/4885TSHR 4681/4885BTN3A1 1740/4885 |
| US-20100204184-A1 | Phosphonates useful as modulators of T-gamma-9-delta-2 activity | CD4, PRKCD, PRKCZ | PPARD 293/4885TSHR 1416/4885BTN3A1 417/4885 |
| US-20060241087-A1 | Phosphonates useful as modulators of t $g(g)9$g(d)2 lymphocyte activity | CD4, GNG2, PLCG2 | PPARD 529/4885TSHR 2353/4885BTN3A1 797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.