Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 10/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 10/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24630687 | 0.85 | KCNH2 (0.33) | OPRM1OPRD1OPRK1OPRL1SMN1; SMN2 | |
| SCHEMBL24944391 | 0.81 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1LMNAHPGDXBP1 | |
| SCHEMBL21341396 | 0.78 | ALDH1A1 (0.35) | OPRM1OPRD1OPRK1OPRL1SMN1; SMN2 | |
| SCHEMBL21341332 | 0.75 | HSD11B1 (0.36) | OPRM1OPRD1OPRK1OPRL1SMN1; SMN2 | |
| SCHEMBL24944393 | 0.71 | OPRM1 (0.35) | OPRM1OPRD1OPRK1OPRL1SMN1; SMN2 | |
| SCHEMBL24943824 | 0.71 | CCR9 (0.39) | ALDH1A1HPGDCYP2D6KCNH2MEN1 | |
| SCHEMBL21341337 | 0.70 | KCNH2 (0.33) | ALDH1A1HPGDKCNH2ALOX15HSD17B10 | |
| SCHEMBL21026072 | 0.69 | SCD (0.44) | SMN1; SMN2ALDH1A1LMNAHPGDXBP1 | |
| SCHEMBL21101086 | 0.67 | CNR2 (0.39) | ALDH1A1CYP1A2CYP2C19CNR2KCNH2 | |
| SCHEMBL21341400 | 0.66 | TRPV4 (0.35) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220378743-A1 | METHOD FOR TREATING FATTY LIVER DISEASE AND/OR STEATOHEPATITIS | BEIJING TIDE PHARMACEUTICAL CO., LTD. (CN) | 2022-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220378743-A1 | METHOD FOR TREATING FATTY LIVER DISEASE AND/OR STEATOHEPATITIS | SLC10A1, CYP7A1, FABP1 | OPRM1 1026/4885OPRD1 1545/4885OPRK1 1470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.