Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 1/20 | 0.38 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24630978 | 0.80 | ADRB2 (0.52) | ADRB2KDM4ELMNAPOLBMAPK1 | |
| SCHEMBL11476242 | 0.80 | ADRB2 (0.52) | ADRB2KDM4ELMNAPOLBMAPK1 | |
| SCHEMBL22864145 | 0.76 | HTT (0.46) | KDM4EQPCTHDAC6PRKCIPOLB | |
| SCHEMBL10467019 | 0.76 | PRKCI (0.51) | ADRB2KDM4ELMNAQPCTHDAC6 | |
| SCHEMBL10465746 | 0.75 | PRKCI (0.46) | KDM4EQPCTHDAC6PRKCICYP26A1 | |
| SCHEMBL10467043 | 0.75 | PRKCI (0.46) | KDM4EQPCTHDAC6PRKCICYP26A1 | |
| SCHEMBL22864259 | 0.74 | CCNE1 (0.46) | EPHX1KDM4ENPC1LMNASMYD3 | |
| Norbudrine SCHEMBL29387737 | 0.74 | ADRB2 (0.65) | ADRB2KDM4ELMNAPOLBMAPK1 | |
| Norbudrine SCHEMBL2732733 | 0.74 | ADRB2 (0.65) | ADRB2KDM4ELMNAPOLBMAPK1 | |
| SCHEMBL24631002 | 0.73 | HTT (0.41) | ADRB2KDM4EPRKCIPOLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220315534-A1 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | CURASEN THERAPEUTICS, INC. | 2022-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220315534-A1 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | ADRB2, ADRB1, ADRA2C | EPHX1 1317/4885ADRB2 1/4885KDM4E 4707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.