Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30134806 | 1.00 | CA12 (0.48) | CA12CA9LMNATRPA1TDP1 | |
| SCHEMBL24631371 | 0.72 | ALDH1A1 (0.43) | CA12CA9LMNATRPA1ALDH1A1 | |
| SCHEMBL962986 | 0.71 | MAPT (0.50) | CA12CA9LMNATRPA1TDP1 | |
| SCHEMBL30134836 | 0.71 | CA12 (0.49) | CA12CA9LMNATRPA1ALDH1A1 | |
| SCHEMBL24631402 | 0.71 | CA12 (0.49) | CA12CA9LMNATRPA1ALDH1A1 | |
| SCHEMBL24631636 | 0.68 | ALDH1A1 (0.38) | CA12CA9LMNATRPA1ALDH1A1 | |
| SCHEMBL9949074 | 0.66 | CA12 (0.54) | CA12CA9LMNATRPA1TDP1 | |
| SCHEMBL10094749 | 0.66 | LMNA (0.45) | CA12CA9LMNATRPA1ALDH1A1 | |
| SCHEMBL9363066 | 0.66 | TSHR (0.47) | CA12CA9LMNATDP1ALDH1A1 | |
| SCHEMBL812065 | 0.66 | KDM4E (0.59) | LMNATDP1ALDH1A1L3MBTL1MAP2K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022217265-A1 | TAAR1 AND SEROTONIN MODULATORS, AND PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2022-10-13 | — | — | WO | disclosed |