Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 9/20 | 0.49 |
| ▸ | CA9 | Q16790 | 9/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24631402 | 1.00 | CA12 (0.49) | CA12CA9LMNAALOX5KDM4E | |
| SCHEMBL962986 | 0.85 | MAPT (0.50) | CA12CA9LMNAALOX5KDM4E | |
| SCHEMBL24631636 | 0.83 | ALDH1A1 (0.38) | CA12CA9LMNAALOX5KDM4E | |
| SCHEMBL10094749 | 0.77 | LMNA (0.45) | CA12CA9LMNAALOX5KDM4E | |
| SCHEMBL9949074 | 0.77 | CA12 (0.54) | CA12CA9LMNAALOX5KDM4E | |
| SCHEMBL7770756 | 0.74 | LMNA (0.60) | CA12CA9LMNAKDM4EALDH1A1 | |
| SCHEMBL24631371 | 0.73 | ALDH1A1 (0.43) | CA12CA9LMNAALOX5KDM4E | |
| SCHEMBL29009259 | 0.72 | PDK2 (0.44) | CA12CA9LMNAKDM4EALDH1A1 | |
| SCHEMBL24631663 | 0.71 | CA12 (0.48) | CA12CA9LMNAALOX5KDM4E | |
| SCHEMBL30134806 | 0.71 | CA12 (0.48) | CA12CA9LMNAALOX5KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4319738-A1 | TAAR1 AND SEROTONIN MODULATORS, AND PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | Sunovion Pharmaceuticals Inc. (US) | 2024-02-14 | — | — | EP | disclosed |
| WO-2022217265-A1 | TAAR1 AND SEROTONIN MODULATORS, AND PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2022-10-13 | — | — | WO | disclosed |