Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4309225 | 0.87 | HRH3 (0.41) | HRH3LMNAALDH1A1TAAR1ALOX15 | |
| SCHEMBL6910596 | 0.84 | HTR6 (0.36) | HRH3CHRM2CHRM1HTR6 | |
| SCHEMBL15061864 | 0.78 | HRH3 (0.37) | HRH3LMNAALDH1A1TAAR1ALOX15 | |
| SCHEMBL7781755 | 0.77 | HTR6 (0.40) | HRH3CHRM2CHRM1HTR6 | |
| SCHEMBL5788565 | 0.77 | CYP1A2 (0.35) | HRH3LMNAALDH1A1TAAR1ALOX15 | |
| SCHEMBL2354448 | 0.75 | HTR6 (0.57) | HRH3LMNAALDH1A1L3MBTL1MEN1 | |
| SCHEMBL27943263 | 0.73 | HTR6 (0.60) | HRH3LMNAALDH1A1TAAR1ALOX15 | |
| SCHEMBL5004055 | 0.71 | HTR6 (0.38) | HRH3LMNAALDH1A1TAAR1L3MBTL1 | |
| SCHEMBL5003994 | 0.70 | MAPT (0.41) | LMNAALDH1A1TAAR1MEN1KMT2A | |
| SCHEMBL5000284 | 0.70 | L3MBTL1 (0.37) | HRH3LMNAALDH1A1TAAR1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011109241-A1 | ACTIVATION OF MONOCYCLOPENTADIENYL GROUP 6 COMLEXES | EQUISTAR CHEMICALS LP (US) | 2011-09-09 | — | — | WO | disclosed |
| US-20110213107-A1 | Activation of monocyclopentadienyl group 6 complexes | EQUISTAR CHEMICALS, LP | 2011-09-01 | — | — | US | disclosed |
| US-20110213107-A1 | Activation of monocyclopentadienyl group 6 complexes | EQUISTAR CHEMICALS, LP | 2011-09-01 | — | — | US | disclosed |