Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2581668 | 1.00 | KMT2A (0.43) | KMT2AALDH1A1MEN1KDM4EHSD17B10 | |
| SCHEMBL2466748 | 0.95 | KMT2A (0.43) | KMT2AALDH1A1MEN1KDM4EHSD17B10 | |
| SCHEMBL2588737 | 0.95 | KMT2A (0.43) | KMT2AALDH1A1MEN1KDM4EHSD17B10 | |
| SCHEMBL2464367 | 0.93 | ALDH1A1 (0.44) | KMT2AALDH1A1MEN1KDM4EHSD17B10 | |
| SCHEMBL2464475 | 0.83 | ALDH1A1 (0.46) | KMT2AALDH1A1MEN1KDM4EHSD17B10 | |
| SCHEMBL2589225 | 0.80 | CA9 (0.47) | KMT2AALDH1A1MEN1KDM4ENPC1 | |
| SCHEMBL15472216 | 0.79 | NPC1 (0.40) | KMT2AMEN1KDM4ENPC1RAB9A | |
| SCHEMBL27825249 | 0.77 | CTNNB1 (0.42) | KMT2AMEN1KDM4EHSD17B10NPC1 | |
| SCHEMBL7912438 | 0.77 | CTNNB1 (0.35) | KMT2AMEN1NPC1RAB9ACTNNB1 | |
| SCHEMBL2461062 | 0.76 | KDM4E (0.42) | KMT2AALDH1A1MEN1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364298-A1 | Quinolone compound and pharmaceutical composition | Otsuka Pharmaceutical Co., Ltd. (JP) | 2011-09-14 | — | — | EP | disclosed |
| WO-2010064735-A1 | QUINOLONE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |