SCHEMBL2581668

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2463263	1.00	KMT2A (0.43)	KMT2AALDH1A1MEN1KDM4EHSD17B10
	SCHEMBL2466748	0.95	KMT2A (0.43)	KMT2AALDH1A1MEN1KDM4EHSD17B10
	SCHEMBL2588737	0.95	KMT2A (0.43)	KMT2AALDH1A1MEN1KDM4EHSD17B10
	SCHEMBL2464367	0.93	ALDH1A1 (0.44)	KMT2AALDH1A1MEN1KDM4EHSD17B10
	SCHEMBL2464475	0.83	ALDH1A1 (0.46)	KMT2AALDH1A1MEN1KDM4EHSD17B10
	SCHEMBL2589225	0.80	CA9 (0.47)	KMT2AALDH1A1MEN1KDM4ENPC1
	SCHEMBL15472216	0.79	NPC1 (0.40)	KMT2AMEN1KDM4ENPC1RAB9A
	SCHEMBL27825249	0.77	CTNNB1 (0.42)	KMT2AMEN1KDM4EHSD17B10NPC1
	SCHEMBL7912438	0.77	CTNNB1 (0.35)	KMT2AMEN1NPC1RAB9ACTNNB1
	SCHEMBL2461062	0.76	KDM4E (0.42)	KMT2AALDH1A1MEN1KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.