Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAT2A | P31153 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL253247 | 0.84 | KDM4E (0.41) | KDM4EALOX15HSD17B10MAPTNOTUM | |
| SCHEMBL20503072 | 0.83 | MAPT (0.52) | KDM4EHSD17B10MAPTSMN1; SMN2KMT2A | |
| SCHEMBL17427353 | 0.81 | KDM4E (0.49) | KDM4EALOX15HSD17B10MAPTNOTUM | |
| SCHEMBL17427352 | 0.81 | NOTUM (0.44) | KDM4EALOX15HSD17B10NOTUMSMN1; SMN2 | |
| SCHEMBL248654 | 0.77 | GSK3A (0.47) | KDM4EMAPTSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL16022003 | 0.76 | HCAR1 (0.40) | KDM4EALOX15HSD17B10NOTUMSMN1; SMN2 | |
| SCHEMBL17427362 | 0.70 | L3MBTL1 (0.47) | KDM4EHSD17B10NOTUMSMN1; SMN2KMT2A | |
| SCHEMBL17427349 | 0.68 | MDM2 (0.51) | NOTUMKMT2AALDH1A1NPSR1HTT | |
| SCHEMBL14877428 | 0.68 | TP53 (0.44) | KDM4EMAPTNOTUMSMN1; SMN2HIF1A | |
| SCHEMBL14966907 | 0.68 | KMT2A (0.49) | KDM4ENOTUMSMN1; SMN2KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105198861-B | 6- acyl group -1,2,4- triazine -3,5- derovatives and herbicide | FMC公司 | 2019-11-22 | — | — | CN | disclosed |
| US-20190047968-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | FMC CORP (US) | 2019-02-14 | — | — | US | disclosed |
| US-10081608-B2 | 6-acyl-1,2,4-triazine-3,5-dione derivative and herbicides | FMC CORPORATION (US) | 2018-09-25 | — | — | US | disclosed |
| US-20170129861-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2017-05-11 | — | — | US | disclosed |
| US-9573909-B2 | 6-acyl-1,2,4-triazine-3,5-dione derivative and herbicides | FMC CORPORATION (US) | 2017-02-21 | — | — | US | disclosed |
| EP-3020709-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | FMC CORPORATION (US) | 2016-05-18 | — | — | EP | disclosed |
| EP-2542538-B1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | FMC CORP (US) | 2015-12-30 | — | — | EP | disclosed |
| US-20150203457-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2015-07-23 | — | — | US | disclosed |
| US-8969554-B2 | 6-acyl-1,2,4-triazine-3,5-dione derivative and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2015-03-03 | — | — | US | disclosed |
| US-20130102468-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2013-04-25 | — | — | US | disclosed |
| EP-2542538-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | Kumiai Chemical Industry Co., Ltd. (JP) | 2013-01-09 | — | — | EP | disclosed |
| WO-2012002096-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10081608-B2 | 6-acyl-1,2,4-triazine-3,5-dione derivative and herbicides | DDT, AADAC, DAZAP1 | KDM4E 900/4885ALOX15 697/4885HSD17B10 230/4885 |
| US-20170129861-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | DDT, AADAC, DAZAP1 | KDM4E 900/4885ALOX15 697/4885HSD17B10 230/4885 |
| US-20150203457-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | DDT, AADAC, DAZAP1 | KDM4E 900/4885ALOX15 697/4885HSD17B10 230/4885 |
| US-20130102468-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | CBR3, DDT, CBR1 | KDM4E 1571/4885ALOX15 185/4885HSD17B10 440/4885 |
| US-20190047968-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | DDT, AADAC, DAZAP1 | KDM4E 900/4885ALOX15 697/4885HSD17B10 230/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.