Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAT2A | P31153 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL246360 | 0.84 | KDM4E (0.45) | KDM4EALOX15HSD17B10MAPTCXCR3 | |
| SCHEMBL254436 | 0.80 | GSK3A (0.41) | KDM4EMAPTKMT2AALDH1A1HPGD | |
| SCHEMBL254120 | 0.70 | GSK3A (0.39) | KDM4EHIF1AKMT2AALDH1A1HTT | |
| SCHEMBL20503072 | 0.69 | MAPT (0.52) | KDM4EHSD17B10MAPTSMN1; SMN2KMT2A | |
| SCHEMBL17427353 | 0.65 | KDM4E (0.49) | KDM4EALOX15HSD17B10MAPTNOTUM | |
| SCHEMBL17427352 | 0.65 | NOTUM (0.44) | KDM4EALOX15HSD17B10NOTUMSMN1; SMN2 | |
| SCHEMBL20604178 | 0.64 | MAPT (0.80) | KDM4EALOX15HSD17B10MAPTNOTUM | |
| SCHEMBL30619347 | 0.63 | ALDH1A1 (0.62) | KDM4EALOX15HSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL15557582 | 0.63 | HTR3A (0.54) | HIF1ANPSR1 | |
| SCHEMBL248654 | 0.61 | GSK3A (0.47) | KDM4EMAPTSMN1; SMN2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2542538-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | Kumiai Chemical Industry Co., Ltd. (JP) | 2013-01-09 | — | — | EP | disclosed |
| WO-2012002096-A1 | 6-ACYL-1,2,4-TRIAZINE-3,5-DIONE DERIVATIVE AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-01-05 | — | — | WO | disclosed |