Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HPD | P32754 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16022003 | 0.92 | HCAR1 (0.40) | NOTUMSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL17427362 | 0.88 | L3MBTL1 (0.47) | NOTUMSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL17427353 | 0.85 | KDM4E (0.49) | NOTUMSMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL248654 | 0.81 | GSK3A (0.47) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL17430272 | 0.81 | NPSR1 (0.56) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL246360 | 0.81 | KDM4E (0.45) | NOTUMSMN1; SMN2ALDH1A1KMT2AGAA | |
| SCHEMBL14966907 | 0.78 | KMT2A (0.49) | NOTUMSMN1; SMN2NPC1KMT2AKDM4E | |
| SCHEMBL16022130 | 0.77 | GRM4 (0.43) | NOTUMKMT2AMEN1LMNA | |
| SCHEMBL17427356 | 0.77 | POLB (0.48) | NPC1RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL17427364 | 0.73 | ALDH1A1 (0.41) | NOTUMALDH1A1GAAKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160009693-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2016-01-14 | — | — | US | disclosed |
| US-20160009693-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2016-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009693-A1 | HERBICIDAL COMPOUNDS | DDT, HAX1, CYP4X1 | NOTUM 166/4885SMN1; SMN2 4026/4885NPC1 4146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.