SCHEMBL24636607

SCHEMBL24636607

CCC(C)[C@H](C)Nc1ccc(C(C)(C)C)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
TP53 P04637 2/20 0.45
ALDH1A1 P00352 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
HSP90AA1 P07900 1/20 0.45
CYP3A4 P08684 1/20 0.45
THRB P10828 1/20 0.45
ALOX15 P16050 1/20 0.45
CASP1 P29466 1/20 0.45
HIF1A Q16665 1/20 0.45
HSD17B10 Q99714 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
GRIA4 P48058 4/20 0.39
HTT P42858 2/20 0.37
ALPL P05186 1/20 0.37
GAA P10253 1/20 0.37
EPHX2 P34913 1/20 0.36
NR1H4 Q96RI1 1/20 0.36
MEN1 O00255 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23377502 0.84 CA1 (0.45) TSHRL3MBTL1TP53ALDH1A1SMN1; SMN2
SCHEMBL11347493 0.81 TSHR (0.72) TSHRL3MBTL1TP53ALDH1A1SMN1; SMN2
SCHEMBL26005653 0.80 TSHR (0.41) TSHRL3MBTL1TP53ALDH1A1SMN1; SMN2
SCHEMBL5551150 0.79 ALDH1A1 (0.50) TSHRL3MBTL1TP53ALDH1A1SMN1; SMN2
SCHEMBL21799725 0.77 L3MBTL1 (0.48) TSHRL3MBTL1TP53ALDH1A1SMN1; SMN2
SCHEMBL14274177 0.76 LMNA (0.44) TSHRALDH1A1SMN1; SMN2HTTGAA
SCHEMBL8359955 0.76 TDP1 (0.52) TSHRL3MBTL1TP53ALDH1A1SMN1; SMN2
SCHEMBL23987254 0.76 TSHR (0.42) TSHRL3MBTL1TP53ALDH1A1SMN1; SMN2
SCHEMBL1061053 0.74 ALDH1A1 (0.60) TSHRL3MBTL1TP53ALDH1A1SMN1; SMN2
SCHEMBL13382108 0.74 KIF11 (0.46) TSHRL3MBTL1TP53ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022191560-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2022-09-15 WO disclosed