Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23560045 | 0.85 | EPHX1 (0.41) | EPHX1EPHX2SIGMAR1SMN1; SMN2KCNH2 | |
| SCHEMBL891398 | 0.82 | SIGMAR1 (0.50) | EPHX1SIGMAR1SMN1; SMN2HTT | |
| SCHEMBL28057484 | 0.82 | — | — | |
| SCHEMBL22851678 | 0.80 | PIM1 (0.36) | EPHX1EPHX2SIGMAR1KCNH2CACNA1I | |
| SCHEMBL172619 | 0.76 | HTT (0.46) | EPHX1EPHX2SIGMAR1HTT | |
| SCHEMBL14810792 | 0.76 | HTT (0.46) | EPHX1EPHX2SIGMAR1HTT | |
| SCHEMBL19122629 | 0.76 | CHRM3 (0.35) | EPHX1EPHX2SIGMAR1SMN1; SMN2GNAI3 | |
| SCHEMBL19083172 | 0.75 | SIGMAR1 (0.33) | SIGMAR1SMN1; SMN2HRH3HTTGAA | |
| SCHEMBL25927715 | 0.75 | BCHE (0.47) | SMN1; SMN2KCNH2CACNA1IHTT | |
| SCHEMBL14454184 | 0.74 | DRD2 (0.35) | EPHX1EPHX2SMN1; SMN2HRH3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192598-A1 | HETEROCYCLES AND USES THEREOF | KUMQUAT BIOSCIENCES INC. (US) | 2022-09-15 | — | — | WO | disclosed |