Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 3/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA9 | Q16790 | 3/20 | 0.32 |
| ▸ | LPL | P06858 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17113535 | 0.82 | IRAK4 (0.39) | SNCAIDO1TDO2EGFRIRAK4 | |
| Acetic Acid SCHEMBL25322169 | 0.82 | IDO1 (0.37) | SNCAIDO1TDO2AAK1ROCK1 | |
| Acetic Acid SCHEMBL25322175 | 0.81 | IDO1 (0.35) | SNCAIDO1TDO2AAK1EGFR | |
| SCHEMBL28877941 | 0.79 | LPL (0.35) | SNCAIDO1TDO2EGFRPRMT5 | |
| SCHEMBL31752127 | 0.78 | IDO1 (0.39) | SNCAIDO1TDO2EGFRROCK1 | |
| SCHEMBL27007442 | 0.76 | DGAT1 (0.46) | SNCADGAT1IDO1TDO2AAK1 | |
| SCHEMBL28877878 | 0.76 | HDAC8 (0.51) | HDAC8 | |
| SCHEMBL3663499 | 0.75 | FFAR1 (0.45) | DGAT1AAK1CA1CA2CA9 | |
| SCHEMBL24638481 | 0.73 | UCHL1 (0.32) | — | |
| SCHEMBL30730354 | 0.73 | HDAC8 (0.48) | HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115141202-A | Pyrimidopyrazinone compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-04 | — | — | CN | disclosed |