SCHEMBL24640

SCHEMBL24640

Nc1ncnc2nn[nH]c12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 8/20 0.50
PI4K2B Q8TCG2 8/20 0.50
PI4K2A Q9BTU6 8/20 0.50
PI4KB Q9UBF8 8/20 0.50
XDH P47989 2/20 0.50
LRRK2 Q5S007 2/20 0.50
LMNA P02545 2/20 0.50
DRD3 P35462 1/20 0.50
ADORA2A P29274 1/20 0.46
ADORA1 P30542 1/20 0.46
NUDT1 P36639 2/20 0.42
RET P07949 1/20 0.41
ERAP1 Q9NZ08 1/20 0.41
PIK3CD O00329 3/20 0.36
PIK3CA P42336 3/20 0.36
PIK3CB P42338 3/20 0.36
PIK3CG P48736 3/20 0.36
PRKDC P78527 3/20 0.36
TSHR P16473 2/20 0.36
LIMK1 P53667 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29471407 1.00 PI4KA (0.50) PI4KAPI4K2BPI4K2API4KBXDH
Benzene SCHEMBL28791218 0.96 PI4KA (0.47) PI4KAPI4K2BPI4K2API4KBXDH
Purine SCHEMBL28553167 0.80 PI4KA (0.49) PI4KAPI4K2BPI4K2API4KBXDH
SCHEMBL7216713 0.78 TDP1 (0.50) PI4KAPI4K2BPI4K2API4KBXDH
SCHEMBL8652766 0.78 LMNA (0.54) PI4KAPI4K2BPI4K2API4KBXDH
SCHEMBL3445228 0.74 DYRK1A (0.39)
SCHEMBL7644350 0.74
SCHEMBL14322494 0.74 PDPK1 (0.38) XDHLMNA
SCHEMBL5134210 0.68
SCHEMBL30492908 0.68 PTPN11 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 16141 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630827-B2 Antisense oligonucleotides targeting SCN2A for the treatment of SCN1A encephalopathies ROGCON, INC. (US) 2026-05-19 US claimed
CN-122029176-A Containing a plurality of oligonucleotides modified oligonucleotides 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122028913-A Oligonucleotides containing ligands in nucleobases, 2 'or 3' positions 阿达尔克斯制药有限公司 2026-05-12 CN claimed
CN-122029177-A Oligonucleotides containing multiple ligands and/or lipids 阿达尔克斯制药有限公司 2026-05-12 CN claimed
EP-4630009-A1 ANTISENSE RNA (ASRNA) TECHNOLOGY AND USE THEREOF 1Globe Health Institute LLC (US) 2025-10-15 EP claimed
EP-4630010-A1 ASYMMETRIC SHORT DUPLEX RNA WITH INTERSPERSED DEOXYRIBONUCLEOTIDES AS A GENE SILENCING TECHNOLOGY AND USE THEREOF 1Globe Health Institute LLC (US) 2025-10-15 EP claimed
EP-4630008-A1 SHORT DUPLEX RNA WITH INTERSPERSED DEOXYRIBONUCLEOTIDES AS A GENE SILENCING TECHNOLOGY AND USE THEREOF 1Globe Health Institute LLC (US) 2025-10-15 EP claimed
US-20250257360-A1 OLIGONUCLEOTIDE INTERFERENCE TREATMENTS OF PROSTATE CANCER UNIV OKLAHOMA (US) 2025-08-14 US claimed
CN-113151261-B Antisense oligonucleotides as inhibitors of TGF-R signaling 神经视觉医药有限公司 2025-06-17 CN claimed
US-20250179503-A1 METHODS OF USING OLIGOMERIC COMPOUNDS TO TREAT SCN2A-RELATED DISORDERS PRAXIS PREC MEDICINES INC (US) 2025-06-05 US claimed
US-5183732-A Adenine-type grain growth modifier EASTMAN KODAK COMPANY (US) 1993-02-02 US claimed
WO-1992001700-A1 2'-FLUOROFURANOSYL DERIVATIVES AND NOVEL METHOD OF PREPARING 2'-FLUOROPYRIMIDINE AND 2'-FLUOROPURINE NUCLEOSIDES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, U.S. DEPARTMENT OF COMMERCE (US) 1992-02-06 WO claimed
CN-1057652-A A kind of acyclic nucleotide of replacement and method of related intermediates thereof of preparing HOECHST AG (DE) 1992-01-08 CN claimed
EP-0463999-A1 Improvements in or relating to organic compounds SANDOZ LTD. (CH) 1992-01-02 EP claimed
EP-0098122-B1 PROCESSES FOR PRODUCING L-PROLINE BY FERMENTATION KYOWA HAKKO KOGYO CO., LTD. (JP) 1989-05-31 EP claimed
EP-0236935-A2 Carboxylic purine nucleosides, their production and use Takeda Chemical Industries, Ltd. (JP) 1987-09-16 EP claimed
EP-0069507-B1 HYDROCARBON COMPOSITIONS CONTAINING HETEROAROMATIC NITROGEN COMPOUNDS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1986-09-10 EP claimed
EP-0098122-A2 Processes for producing L-proline by fermentation KYOWA HAKKO KOGYO CO., LTD. (JP) 1984-01-11 EP claimed
EP-0069507-A2 Hydrocarbon compositions containing heteroaromatic nitrogen compounds EXXON RESEARCH AND ENGINEERING COMPANY (US) 1983-01-12 EP claimed
US-4367152-A Selected heteroaromatic nitrogen compounds as antioxidant/metal deactivators/electrical insulators in lubricating oils and petroleum liquid fuels EXXON RESEARCH AND ENGINEERING CO. (US) 1983-01-04 US claimed