Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.54 |
| ▸ | PI4KA | P42356 | 2/20 | 0.54 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.54 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.54 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | XDH | P47989 | 1/20 | 0.54 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 5/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29420373 | 0.81 | CYP3A4 (0.62) | LMNAPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL160074 | 0.81 | CYP3A4 (0.62) | LMNAPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL29471407 | 0.78 | PI4KA (0.50) | LMNAPI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL24640 | 0.78 | PI4KA (0.50) | LMNAPI4KAPI4K2BPI4K2API4KB | |
| Benzene SCHEMBL28791218 | 0.75 | PI4KA (0.47) | LMNAPI4KAPI4K2BPI4K2API4KB | |
| Adenine SCHEMBL385842 | 0.73 | LMNA (0.92) | LMNAPI4KAPI4K2BPI4K2API4KB | |
| Adenine SCHEMBL29077040 | 0.73 | PI4KA (0.92) | LMNAPI4KAPI4K2BPI4K2API4KB | |
| Adenine SCHEMBL29242838 | 0.73 | LMNA (0.71) | LMNAPI4KAPI4K2BPI4K2API4KB | |
| Adenine SCHEMBL8111 | 0.73 | PI4KA (1.00) | LMNAPI4KAPI4K2BPI4K2API4KB | |
| Adenine SCHEMBL3414606 | 0.73 | PI4KA (1.00) | LMNAPI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763208-A | Oligonucleotides and their analogs capable of passive cell membrane permeation | GILEAD SCIENCES, INC. (US) | 1998-06-09 | — | — | US | disclosed |
| US-5633360-A | CONTAINS AT LEAST TWO NUCLEOSIDE RESIDUES AND INTERNUCLEOTIDE LINKAGES | GILEAD SCIENCES, INC. (US) | 1997-05-27 | — | — | US | disclosed |