Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24640705 | 0.88 | HRH3 (0.35) | HRH3KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL24640241 | 0.88 | HRH3 (0.35) | HRH3KDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL24640240 | 0.83 | HRH3 (0.36) | HRH3MDM2 | |
| SCHEMBL24640235 | 0.83 | HRH3 (0.33) | HRH3 | |
| SCHEMBL24640200 | 0.83 | HRH3 (0.36) | HRH3MDM2 | |
| SCHEMBL24640238 | 0.82 | DRD2 (0.35) | HRH3 | |
| SCHEMBL24640697 | 0.82 | HRH3 (0.31) | HRH3 | |
| SCHEMBL24640186 | 0.79 | — | — | |
| SCHEMBL24640782 | 0.77 | HRH3 (0.37) | HRH3KMT2AKCNN4 | |
| SCHEMBL24640776 | 0.77 | HRH3 (0.37) | HRH3KMT2AKCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170974-A1 | TRICYCLIC DERIVATIVES USEFUL AS PARP7 INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-08-18 | — | — | WO | disclosed |