SCHEMBL24640697

SCHEMBL24640697

CC(C)N1CCN2c3ncc(N4CCC4)cc3SC[C@@H]2C1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24640186 0.88
SCHEMBL24640236 0.82 HRH3 (0.32) HRH3
SCHEMBL24640167 0.81 HRH3 (0.31) HRH3
SCHEMBL24640248 0.80 HTR3A (0.34) HRH3
SCHEMBL24640240 0.80 HRH3 (0.36) HRH3
SCHEMBL24640235 0.80 HRH3 (0.33) HRH3
SCHEMBL24640200 0.80 HRH3 (0.36) HRH3
SCHEMBL24640238 0.79 DRD2 (0.35) HRH3
SCHEMBL24640618 0.78 TIPARP (0.34) HRH3
SCHEMBL24639260 0.78 TIPARP (0.34) HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022170974-A1 TRICYCLIC DERIVATIVES USEFUL AS PARP7 INHIBITORS JACOBIO PHARMACEUTICALS CO., LTD. (CN) 2022-08-18 WO disclosed