Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | SGPL1 | O95470 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24640236 | 0.82 | HRH3 (0.32) | HRH3 | |
| SCHEMBL24640240 | 0.80 | HRH3 (0.36) | DRD3HRH3 | |
| SCHEMBL24640200 | 0.80 | HRH3 (0.36) | DRD3HRH3 | |
| SCHEMBL24640235 | 0.80 | HRH3 (0.33) | HRH3HRH4 | |
| SCHEMBL24640697 | 0.79 | HRH3 (0.31) | HRH3 | |
| SCHEMBL24640710 | 0.78 | DRD2 (0.34) | DRD2DRD3HRH3IRAK4HRH4 | |
| SCHEMBL24640706 | 0.78 | DRD2 (0.34) | DRD2DRD3HRH3IRAK4HRH4 | |
| SCHEMBL31244797 | 0.77 | HTR2A (0.41) | — | |
| SCHEMBL24639978 | 0.76 | DRD2 (0.33) | DRD2DRD3HRH3IRAK4HRH4 | |
| SCHEMBL24639979 | 0.76 | DRD2 (0.33) | DRD2DRD3HRH3IRAK4HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022170974-A1 | TRICYCLIC DERIVATIVES USEFUL AS PARP7 INHIBITORS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-08-18 | — | — | WO | disclosed |