Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | SLC6A9 | P48067 | 7/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTR1E | P28566 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2470759 | 0.89 | GPR139 (0.50) | NPC1SLC6A9SLC6A5ALDH1A1SMN1; SMN2 | |
| SCHEMBL2464573 | 0.84 | NPC1 (0.50) | NPC1SLC6A9SLC6A5ALDH1A1SMN1; SMN2 | |
| SCHEMBL14243987 | 0.83 | SLC6A9 (0.48) | NPC1SLC6A9SLC6A5ALDH1A1SMN1; SMN2 | |
| SCHEMBL2465596 | 0.83 | ALDH1A1 (0.48) | NPC1SLC6A9SLC6A5CTSLALDH1A1 | |
| SCHEMBL2469014 | 0.83 | ALDH1A1 (0.48) | NPC1SLC6A9SLC6A5CTSLALDH1A1 | |
| SCHEMBL2464084 | 0.83 | NPC1 (0.49) | NPC1SLC6A9SLC6A5CTSLALDH1A1 | |
| SCHEMBL2467776 | 0.81 | ALDH1A1 (0.46) | NPC1SLC6A9SLC6A5CTSLALDH1A1 | |
| SCHEMBL2465585 | 0.81 | SLC6A9 (0.46) | NPC1SLC6A9SLC6A5ALDH1A1SMN1; SMN2 | |
| SCHEMBL2467417 | 0.80 | HPGD (0.47) | NPC1SLC6A9CTSLALDH1A1SMN1; SMN2 | |
| SCHEMBL2467907 | 0.80 | NPC1 (0.53) | NPC1SLC6A9SLC6A5ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2539378-B1 | HALOGENATED AMIDE ESTER AND INTERNAL ELECTRON DONOR WITH SAME | GRACE W R & CO (US) | 2018-06-06 | — | — | EP | disclosed |
| EP-2539378-A1 | HALOGENATED AMIDE ESTER AND INTERNAL ELECTRON DONOR WITH SAME | Dow Global Technologies LLC (US) | 2013-01-02 | — | — | EP | disclosed |
| WO-2011106497-A1 | HALOGENATED AMIDE ESTER AND INTERNAL ELECTRON DONOR WITH SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-09-01 | — | — | WO | disclosed |