Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | SCN4A | P35499 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3076538 | 0.95 | SMN1; SMN2 (0.56) | RAB9ASMN1; SMN2HPGDNPC1ALDH1A1 | |
| SCHEMBL24648610 | 0.81 | MAPT (0.53) | RAB9ASMN1; SMN2HPGDNPC1ALDH1A1 | |
| SCHEMBL24648645 | 0.81 | SMN1; SMN2 (0.56) | RAB9ASMN1; SMN2HPGDNPC1ALDH1A1 | |
| SCHEMBL24648637 | 0.79 | MAPT (0.60) | RAB9ASMN1; SMN2HPGDNPC1ALDH1A1 | |
| SCHEMBL24648640 | 0.78 | SMN1; SMN2 (0.49) | RAB9ASMN1; SMN2HPGDNPC1ALDH1A1 | |
| SCHEMBL8514102 | 0.77 | MAPT (0.60) | RAB9ASMN1; SMN2HPGDNPC1ALDH1A1 | |
| SCHEMBL24648681 | 0.76 | SMN1; SMN2 (0.52) | RAB9ASMN1; SMN2HPGDNPC1ALDH1A1 | |
| SCHEMBL2709859 | 0.74 | NPC1 (0.74) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL24648717 | 0.74 | RAB9A (0.49) | RAB9ASMN1; SMN2HPGDNPC1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL334836 | 0.73 | NPC1 (0.72) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12570647-B2 | Amino benzothiazole compounds for treatment of antibiotic resistant bacteria | SAINT LOUIS UNIVERSITY (US) | 2026-03-10 | — | — | US | disclosed |
| US-20220267312-A1 | AMINO BENZOTHIAZOLE COMPOUNDS FOR TREATMENT OF ANTIBIOTIC RESISTANT BACTERIA | SAINT LOUIS UNIVERSITY (US) | 2022-08-25 | — | — | US | disclosed |
| US-20220267312-A1 | AMINO BENZOTHIAZOLE COMPOUNDS FOR TREATMENT OF ANTIBIOTIC RESISTANT BACTERIA | SAINT LOUIS UNIVERSITY (US) | 2022-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220267312-A1 | AMINO BENZOTHIAZOLE COMPOUNDS FOR TREATMENT OF ANTIBIOTIC RESISTANT BACTERIA | BCAT2, BCAT1, ABAT | RAB9A 1446/4885SMN1; SMN2 4059/4885HPGD 1531/4885 |
| US-12570647-B2 | Amino benzothiazole compounds for treatment of antibiotic resistant bacteria | BCAT1, BCAT2, IL4I1 | RAB9A 3461/4885SMN1; SMN2 2823/4885HPGD 3966/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.