SCHEMBL24649405

SCHEMBL24649405

Nc1nc(=O)c2ncn([C@@H]3O[C@@H]4COP(=O)(O)O[C@H]5[C@@H](O)[C@H](n6cnc7c(N)ncnc76)O[C@@H]5COP(=O)(O)O[C@@H]3[C@@H]4O)c2[nH]1

nearest known ligand 0.85

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 18/20 0.85
▸ LMNA P02545 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25063900 1.00 STING1 (0.85) STING1LMNA
SCHEMBL26351022 1.00 STING1 (0.85) STING1LMNA
SCHEMBL25063904 0.94 STING1 (0.78) STING1
SCHEMBL22334110 0.90 STING1 (1.00) STING1
SCHEMBL22434473 0.90 STING1 (1.00) STING1
SCHEMBL22334105 0.90 STING1 (1.00) STING1
SCHEMBL24967640 0.90 STING1 (1.00) STING1
SCHEMBL23477351 0.90 STING1 (1.00) STING1
SCHEMBL21532129 0.90 STING1 (1.00) STING1
SCHEMBL23800770 0.90 STING1 (1.00) STING1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4729068-A1 LENTIVIRAL VECTOR-BASED IMMUNOTHERAPY OF PROSTATE TUMORS Theravectys (FR) 2026-04-22 — — EP claimed
EP-4309739-B1 CORE/SHELL STRUCTURE PLATFORM FOR IMMUNOTHERAPY METHODIST HOSPITAL (US) 2026-04-08 — — EP claimed
EP-3816176-B1 HYDRATE CRYSTAL OF 3',3'-CGAMP YAMASA CORP (JP) 2026-03-04 — — EP claimed
US-12545903-B2 Polypeptide assemblies and methods for the production thereof UNIVERSITY OF WASHINGTON (US) 2026-02-10 — — US claimed
US-20260034159-A1 METHODS FOR PRODUCING CYCLIC DINUCLEOTIDES ALDEVRON LLC (US) 2026-02-05 — — US claimed
US-12533415-B2 Core/shell structure platform for immunotherapy THE METHODIST HOSPITAL (US) 2026-01-27 — — US claimed
US-20250387425-A1 NOVEL PERSONAL NEOANTIGEN VACCINES AND MARKERS ANDA BIOLOGY MEDICINE DEV SHENZHEN CO LTD (CN) 2025-12-25 — — US claimed
US-20250381256-A1 SUBLINGUAL NANOFIBER VACCINES AND METHODS OF MAKING AND USING SAME UNIV DUKE (US) 2025-12-18 — — US claimed
WO-2025242657-A1 LIPOPEPTIDE BUILDING BLOCKS AND AGGREGATES SHAPE BIOPHARMACEUTICALS AG (CH) 2025-11-27 — — WO claimed
US-20250282871-A1 PHARMACEUTICAL COMBINATION AND USE THEREOF TIANJIN LIPOGEN TECH CO LTD (CN) 2025-09-11 — — US claimed
WO-2022215079-A1 NANOVACCINES FOR TREATMENT OF VIRAL DISEASES RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2022-10-13 — — WO claimed
US-20220305103-A1 CORE/SHELL STRUCTURE PLATFORM FOR IMMUNOTHERAPY THE METHODIST HOSPITAL 2022-09-29 — — US claimed
US-20220305048-A1 USE OF HEPARIN TO PROMOTE TYPE 1 INTERFERON SIGNALING DANA-FARBER CANCER INSTITUTE, INC. (US) 2022-09-29 — — US claimed
WO-2022195427-A1 ADJUVANT FOR VACCINE DEVELOPMENT SHEN HAIFA (US) 2022-09-22 — — WO claimed
US-11396524-B2 Hydrate crystal of 3′,3′-cGAMP YAMASA CORPORATION (JP) 2022-07-26 — — US claimed
WO-2022118043-A1 NOVEL PROTEIN-LIGAND COMPLEX ENARA BIO LIMITED (GB) 2022-06-09 — — WO claimed
EP-4008344-A1 CORE/SHELL STRUCTURE PLATFORM FOR IMMUNOTHERAPY The Methodist Hospital (US) 2022-06-08 — — EP claimed
WO-2022103927-A1 IMMUNOGENIC COMPOSITIONS FOR CORONAVIRUSES SHAPE BIOPHARMACEUTICALS INC. (US) 2022-05-19 — — WO claimed
US-20220111029-A1 POLYMERIC NANOVACCINES AND USES THEREOF RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2022-04-14 — — US claimed
WO-2022032043-A1 DENDRITIC CELL ACTIVATING THERAPY AS AN ADJUNCT TO RADIATION THERAPY MONTEFIORE MEDICAL CENTER (US) 2022-02-10 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12533415-B2 Core/shell structure platform for immunotherapy PHOSPHO1, MYD88, PCTP STING1 15/4885LMNA 454/4885
US-11396524-B2 Hydrate crystal of 3′,3′-cGAMP CGAS, GMPS, IAPP STING1 11/4885LMNA 3712/4885
US-20250387425-A1 NOVEL PERSONAL NEOANTIGEN VACCINES AND MARKERS PPP1R15A, STING1, PPP1R15B STING1 2/4885LMNA 3608/4885
US-20220305048-A1 USE OF HEPARIN TO PROMOTE TYPE 1 INTERFERON SIGNALING IFNAR1, IFNG, STAT1 STING1 5/4885LMNA 4309/4885
US-20260034159-A1 METHODS FOR PRODUCING CYCLIC DINUCLEOTIDES CGAS, STING1, IFNG STING1 2/4885LMNA 3885/4885
US-12545903-B2 Polypeptide assemblies and methods for the production thereof PICALM, PHAX, NSF STING1 1387/4885LMNA 1937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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