Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650403 | 0.93 | LMNA (0.39) | PTGDR2TSHRCYSLTR2CYSLTR1FFAR4 | |
| SCHEMBL24650729 | 0.86 | MAPT (0.45) | TSHRADRA1A | |
| SCHEMBL24651005 | 0.85 | TDP1 (0.38) | PTGDR2TSHRADRA1A | |
| SCHEMBL24650412 | 0.84 | PDE4A (0.44) | CYSLTR2CYSLTR1 | |
| SCHEMBL24650741 | 0.84 | ADRA1A (0.41) | PTGDR2TSHRFFAR4ADRA1A | |
| SCHEMBL24650747 | 0.82 | ADRA1A (0.39) | ADRA1A | |
| SCHEMBL24650257 | 0.82 | DRD3 (0.35) | TSHRFFAR4S1PR5 | |
| SCHEMBL24650815 | 0.81 | PTGDR2 (0.41) | PTGDR2TSHRCYSLTR2CYSLTR1FFAR4 | |
| SCHEMBL24650727 | 0.80 | PDE4A (0.38) | TSHRADRA1A | |
| SCHEMBL24650248 | 0.80 | PTGDR2 (0.41) | PTGDR2TSHRFFAR4RAB9AS1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |