Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650832 | 0.94 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DCA1 | |
| SCHEMBL24650256 | 0.92 | L3MBTL1 (0.40) | PDE4APDE4BPDE4CPDE4DACHE | |
| SCHEMBL24651149 | 0.89 | ACHE (0.41) | CA1CA2ACHEDRD2DRD3 | |
| SCHEMBL24650304 | 0.88 | ALDH1A1 (0.42) | CA1CA2ACHEPTPN1SMN1; SMN2 | |
| SCHEMBL24650411 | 0.86 | PDE4A (0.45) | PDE4APDE4BPDE4CPDE4DCA1 | |
| SCHEMBL24650824 | 0.86 | BRD4 (0.43) | PDE4APDE4BPDE4CPDE4DPTPN1 | |
| SCHEMBL24651156 | 0.85 | LMNA (0.43) | CA1CA2ACHEDRD2DRD3 | |
| SCHEMBL24651159 | 0.85 | L3MBTL1 (0.37) | CA1CA2ACHEKMT2AL3MBTL1 | |
| SCHEMBL24650814 | 0.83 | MAPT (0.42) | PDE4APDE4BPDE4CPDE4DCA1 | |
| SCHEMBL24650744 | 0.83 | PDE4B (0.47) | PDE4APDE4BPDE4CPDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |