Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.37 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650329 | 0.96 | DRD2 (0.38) | DRD2DRD3HPGDMTNR1ATSHR | |
| SCHEMBL24650298 | 0.91 | DRD2 (0.40) | DRD2DRD3GAATSHR | |
| SCHEMBL24650340 | 0.84 | S1PR5 (0.41) | DRD2DRD3 | |
| SCHEMBL24650954 | 0.84 | HPGD (0.36) | CYP4F2CYP4A11NR5A2NR5A1HPGD | |
| SCHEMBL24650352 | 0.84 | CYP4F2 (0.49) | CYP4F2CYP4A11DRD2GAA | |
| SCHEMBL24650927 | 0.83 | HPGD (0.36) | CYP4F2CYP4A11DRD2DRD3NR5A2 | |
| SCHEMBL24650294 | 0.83 | DRD2 (0.41) | DRD2DRD3LMNAMTNR1AMTNR1B | |
| SCHEMBL24651027 | 0.81 | ADRA1A (0.54) | NR5A2NR5A1HPGDHDAC1HDAC6 | |
| SCHEMBL24651017 | 0.81 | DRD2 (0.34) | DRD2DRD3NR5A2NR5A1HPGD | |
| SCHEMBL24650333 | 0.80 | S1PR5 (0.44) | DRD2DRD3HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |