Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650300 | 0.93 | ALDH1A1 (0.55) | CYP4F2CYP4A11ALDH1A1GAACYP1A2 | |
| SCHEMBL24650329 | 0.88 | DRD2 (0.38) | ALDH1A1DRD2NOTUM | |
| SCHEMBL24650296 | 0.85 | PKM (0.40) | CYP4F2CYP4A11ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL24650341 | 0.84 | CYP4F2 (0.39) | CYP4F2CYP4A11GAADRD2 | |
| SCHEMBL24650957 | 0.84 | CYP1A2 (0.50) | CYP4F2CYP4A11ALDH1A1GAACYP1A2 | |
| SCHEMBL24650929 | 0.83 | CYP4F2 (0.47) | CYP4F2CYP4A11ALDH1A1GAACYP1A2 | |
| SCHEMBL15078827 | 0.82 | ALDH1A1 (0.55) | CYP4F2CYP4A11ALDH1A1GAADRD2 | |
| SCHEMBL24650456 | 0.82 | PDE4A (0.42) | GAADRD2NAMPTSMYD3TDP1 | |
| SCHEMBL24651014 | 0.82 | CYP4F2 (0.40) | CYP4F2CYP4A11ALDH1A1GAACYP1A2 | |
| SCHEMBL24650333 | 0.82 | S1PR5 (0.44) | SMN1; SMN2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |