Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13256061 | 0.70 | NAMPT (0.41) | BRD4ALDH1A1 | |
| SCHEMBL8981963 | 0.70 | BRD4 (0.56) | BRD4HPGD | |
| SCHEMBL9305655 | 0.70 | BRD4 (0.60) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14337193 | 0.70 | HTR2A (0.51) | BRD4MTNR1BMTNR1ANQO2 | |
| Hydrochloric Acid SCHEMBL9304134 | 0.69 | BRD4 (0.58) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5545270 | 0.69 | KDM4E (0.54) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL12698684 | 0.68 | ALDH1A1 (0.67) | BRD4PTPN1MTNR1BALDH1A1TSHR | |
| SCHEMBL21601607 | 0.68 | PTPN1 (0.53) | BRD4PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10321961 | 0.67 | DRD2 (0.47) | — | |
| SCHEMBL4637019 | 0.67 | DRD2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |