Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650996 | 0.88 | L3MBTL1 (0.53) | POLBSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL24650389 | 0.87 | HMGCR (0.50) | KMT2AALDH1A1PTGDR2CA1CA2 | |
| SCHEMBL24650385 | 0.85 | LMNA (0.51) | KMT2AALDH1A1PTGDR2CA1CA2 | |
| SCHEMBL24650743 | 0.84 | TSHR (0.44) | ALDH1A1PTGDR2TSHRLMNA | |
| SCHEMBL24650995 | 0.83 | FYN (0.52) | POLBSMN1; SMN2ALDH1A1PTGDR2KDM4E | |
| SCHEMBL24650395 | 0.83 | ALDH1A1 (0.51) | POLBKMT2AALDH1A1KDM4ETSHR | |
| Hydrochloric Acid SCHEMBL4780777 | 0.81 | PKM (0.47) | POLBPTGDR2CA1CA2ALOX15 | |
| SCHEMBL3041826 | 0.80 | ADRA1A (0.56) | ALDH1A1CA1CA2ALOX15 | |
| SCHEMBL24650378 | 0.79 | CA1 (0.42) | POLBSMN1; SMN2MEN1KMT2APTGDR2 | |
| SCHEMBL24650909 | 0.79 | ADRA1A (0.64) | POLBSMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |