Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | DRD3 | P35462 | 4/20 | 0.33 |
| ▸ | DRD1 | P21728 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650255 | 0.89 | CYSLTR2 (0.36) | PTGDR2ADRA1AL3MBTL1CYP2C19TSHR | |
| SCHEMBL24650390 | 0.89 | LMNA (0.46) | LMNAPTGDR2ADRA1AL3MBTL1DRD3 | |
| SCHEMBL24650734 | 0.88 | ADRA1A (0.36) | ADRA1AL3MBTL1DRD3DRD1HPGD | |
| SCHEMBL24650740 | 0.88 | BRD4 (0.38) | ADRA1AL3MBTL1DRD3DRD1KDM4E | |
| SCHEMBL24651006 | 0.88 | GLA (0.46) | LMNAPTGDR2ADRA1AL3MBTL1ALDH1A1 | |
| SCHEMBL24650748 | 0.85 | MAPT (0.43) | ADRA1AL3MBTL1DRD3DRD1HPGD | |
| SCHEMBL24650408 | 0.85 | BRD4 (0.45) | L3MBTL1AGTR2 | |
| SCHEMBL24650254 | 0.83 | L3MBTL1 (0.37) | ADRA1AL3MBTL1DRD3DRD1KDM4E | |
| SCHEMBL24650741 | 0.83 | ADRA1A (0.41) | LMNAPTGDR2ADRA1ADRD3DRD1 | |
| SCHEMBL24650403 | 0.82 | LMNA (0.39) | LMNAPTGDR2ADRA1AL3MBTL1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |