Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.31 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.31 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24650751 | 0.93 | PTGDR2 (0.40) | PTGDR2ADRA1ATSHRS1PR5CYSLTR2 | |
| SCHEMBL24651005 | 0.86 | TDP1 (0.38) | PTGDR2ADRA1AL3MBTL1TSHR | |
| SCHEMBL24650747 | 0.86 | ADRA1A (0.39) | ADRA1ADRD2DRD3 | |
| SCHEMBL24650727 | 0.84 | PDE4A (0.38) | ADRA1AL3MBTL1TSHR | |
| SCHEMBL24650390 | 0.83 | LMNA (0.46) | LMNAPTGDR2ADRA1AL3MBTL1DRD2 | |
| SCHEMBL24650449 | 0.82 | LMNA (0.47) | LMNADRD2DRD3S1PR5 | |
| SCHEMBL24650729 | 0.82 | MAPT (0.45) | ADRA1ADRD2DRD3TSHR | |
| SCHEMBL24650397 | 0.82 | LMNA (0.39) | LMNAPTGDR2ADRA1AL3MBTL1DRD2 | |
| SCHEMBL24651157 | 0.81 | LMNA (0.41) | LMNAPTGDR2ADRA1AL3MBTL1DRD2 | |
| SCHEMBL24651147 | 0.80 | PTGDR2 (0.40) | LMNAPTGDR2L3MBTL1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022238507-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2022-11-17 | — | — | WO | disclosed |