Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL704360 | 0.89 | TACR1 (0.46) | GPR35L3MBTL1ALDH1A1HTTTACR1 | |
| SCHEMBL20346364 | 0.85 | NOTUM (0.50) | GPR35L3MBTL1ALDH1A1HTTTACR1 | |
| SCHEMBL24650659 | 0.85 | GPR35 (0.43) | GPR35L3MBTL1ALDH1A1HTTTACR1 | |
| SCHEMBL137510 | 0.84 | HSP90AB1 (0.47) | GPR35L3MBTL1ALDH1A1HTTTACR1 | |
| SCHEMBL10218953 | 0.83 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1HTTLMNAMAPT | |
| SCHEMBL20349610 | 0.81 | RXRA (0.50) | GPR35L3MBTL1ALDH1A1HTTTACR1 | |
| SCHEMBL10218934 | 0.80 | CYP4F2 (0.47) | L3MBTL1ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL5092006 | 0.78 | LMNA (0.46) | ALDH1A1HTTLMNAMAPTPOLB | |
| SCHEMBL701131 | 0.78 | ALDH1A1 (0.61) | L3MBTL1ALDH1A1HTTMAPTSMN1; SMN2 | |
| SCHEMBL136465 | 0.77 | RXRA (0.39) | GPR35L3MBTL1ALDH1A1HTTTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212326-A1 | NEK7 INHIBITORS | Halia Therapeutics, Inc. (US) | 2022-10-06 | — | — | WO | disclosed |