Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK1 | P49759 | 2/20 | 0.34 |
| ▸ | CLK2 | P49760 | 2/20 | 0.34 |
| ▸ | NNMT | P40261 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
| ▸ | LGMN | Q99538 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1473350 | 0.82 | MAPT (0.35) | CLK1CLK2SMN1; SMN2NPC1TP53 | |
| SCHEMBL12775299 | 0.81 | NNMT (0.55) | NNMTSMN1; SMN2 | |
| SCHEMBL12227502 | 0.81 | UBE2T (0.45) | — | |
| SCHEMBL24016755 | 0.81 | NPC1 (0.34) | CLK1CLK2SMN1; SMN2NPC1TP53 | |
| SCHEMBL14206340 | 0.81 | TRPV4 (0.48) | MLYCD | |
| SCHEMBL1474288 | 0.78 | CLK1 (0.33) | CLK1CLK2SMN1; SMN2NPC1TP53 | |
| SCHEMBL20304778 | 0.75 | POLB (0.47) | CLK1CLK2NNMTSMN1; SMN2NPC1 | |
| SCHEMBL5366444 | 0.74 | KCNJ1 (0.44) | CLK1CLK2SMN1; SMN2NPC1TP53 | |
| SCHEMBL1070876 | 0.74 | P4HA1 (0.55) | SMN1; SMN2MAPT | |
| SCHEMBL17033581 | 0.74 | HDAC1 (0.50) | NNMTSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220308056-A1 | BIOMARKER FOR ASSESSING THE RISK OF DEVELOPING ACUTE COVID-19 AND POST-ACUTE COVID-19 | OMEROS CORPORATION | 2022-09-29 | — | — | US | disclosed |