Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28515905 | 0.76 | SLC27A2 (0.46) | MAPTL3MBTL1HTR6KMT2AMEN1 | |
| SCHEMBL29619573 | 0.76 | SLC27A2 (0.46) | MAPTL3MBTL1HTR6KMT2AMEN1 | |
| SCHEMBL29619591 | 0.76 | ALDH1A1 (0.39) | HTR6KMT2AMEN1ALDH1A1 | |
| SCHEMBL29619607 | 0.76 | HTR6 (0.39) | MAPTHTR6KMT2AMMP2MMP9 | |
| SCHEMBL28522164 | 0.74 | TP53 (0.42) | MAPTL3MBTL1HTR6KMT2AMEN1 | |
| SCHEMBL29619616 | 0.69 | LMNA (0.40) | MAPTL3MBTL1KMT2AMEN1CYP1A2 | |
| SCHEMBL28528531 | 0.69 | LMNA (0.42) | MAPTL3MBTL1KMT2AMEN1CYP1A2 | |
| SCHEMBL28526734 | 0.67 | LMNA (0.42) | MAPTL3MBTL1HTR6KMT2AMEN1 | |
| SCHEMBL24654091 | 0.67 | HTR6 (0.38) | MAPTHTR6KMT2AMEN1TSHR | |
| SCHEMBL29619626 | 0.67 | HTR6 (0.38) | MAPTHTR6KMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022082817-A1 | 3-THREE-MEMBERED SPIROOXINDOLE DERIVATIVE SYNTHESIZING METHOD | 苏州大学 | 2022-04-28 | — | — | WO | disclosed |