Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MLYCD | O95822 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2462153 | 0.94 | HPGD (0.47) | RAB9AALDH1A1NPC1LMNAALOX12 | |
| SCHEMBL2469849 | 0.90 | RAB9A (0.48) | RAB9AALDH1A1NPC1LMNAALOX12 | |
| SCHEMBL2466872 | 0.88 | RAB9A (0.47) | RAB9AALDH1A1NPC1LMNAALOX12 | |
| SCHEMBL14243819 | 0.87 | RAB9A (0.46) | RAB9AALDH1A1NPC1LMNAALOX12 | |
| SCHEMBL2465596 | 0.87 | ALDH1A1 (0.48) | RAB9AALDH1A1NPC1LMNAALOX12 | |
| SCHEMBL2466807 | 0.85 | RAB9A (0.44) | RAB9AALDH1A1NPC1LMNAALOX12 | |
| SCHEMBL2465532 | 0.85 | RAB9A (0.44) | RAB9AALDH1A1NPC1LMNAALOX12 | |
| SCHEMBL2468306 | 0.84 | GPR139 (0.51) | RAB9AALDH1A1NPC1LMNAALOX12 | |
| SCHEMBL2470759 | 0.83 | GPR139 (0.50) | RAB9AALDH1A1NPC1LMNAALOX12 | |
| SCHEMBL2467417 | 0.81 | HPGD (0.47) | RAB9AALDH1A1NPC1LMNAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2539378-B1 | HALOGENATED AMIDE ESTER AND INTERNAL ELECTRON DONOR WITH SAME | GRACE W R & CO (US) | 2018-06-06 | — | — | EP | disclosed |
| US-8466081-B2 | Halogenated amide ester and internal electron donor with same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-06-18 | — | — | US | disclosed |
| EP-2539378-A1 | HALOGENATED AMIDE ESTER AND INTERNAL ELECTRON DONOR WITH SAME | Dow Global Technologies LLC (US) | 2013-01-02 | — | — | EP | disclosed |
| US-20120322964-A1 | Halogenated Amide Ester and Internal Electron Donor with Same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-12-20 | — | — | US | disclosed |
| WO-2011106497-A1 | HALOGENATED AMIDE ESTER AND INTERNAL ELECTRON DONOR WITH SAME | DOW GLOBAL TECHNOLOGIES LLC (US) | 2011-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120322964-A1 | Halogenated Amide Ester and Internal Electron Donor with Same | NAT10, NAT1, NAA50 | RAB9A 2431/4885ALDH1A1 701/4885NPC1 299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.