Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13239906 | 0.77 | PDE4A (0.34) | GAACYP2C19CYP1A2PDE4ATDP1 | |
| SCHEMBL2745624 | 0.74 | TLR8 (0.33) | — | |
| SCHEMBL2773009 | 0.72 | NOS1 (0.36) | ALDH1A1TERTGAACYP2C19CYP1A2 | |
| SCHEMBL15951407 | 0.72 | HSD17B10 (0.37) | ALDH1A1CYP2C19CYP1A2PDE4ATDP1 | |
| SCHEMBL29989740 | 0.72 | LMNA (0.39) | ALDH1A1CYP2C19CYP1A2PDE4ATDP1 | |
| SCHEMBL10485343 | 0.72 | TRIM58 (0.36) | ALDH1A1GAACYP2C19CYP1A2PDE4A | |
| SCHEMBL11713959 | 0.72 | ALDH1A1 (0.33) | ALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL33146 | 0.71 | PDE4A (0.48) | ALDH1A1GAACYP2C19CYP1A2PDE4A | |
| SCHEMBL3561446 | 0.71 | HPGD (0.31) | L3MBTL1TERT | |
| SCHEMBL10896684 | 0.71 | PDE4A (0.39) | ALDH1A1TERTGAACYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234271-A1 | HETEROARYL COMPOUNDS USEFUL IN THE TREATMENT OF COGNITIVE DISORDERS | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2022-11-10 | — | — | WO | disclosed |