Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22388515 | 0.73 | PRKCI (0.49) | PRKCICYP2A6CHRNA7ABL1SRC | |
| SCHEMBL19499088 | 0.73 | KCNH2 (0.34) | PRKCIKCNH2CYP1A2CYP3A4TSHR | |
| SCHEMBL2627061 | 0.73 | PRKCI (0.55) | PRKCICYP2A6ABL1SRCKCNH2 | |
| SCHEMBL18710631 | 0.71 | PRKCI (0.46) | PRKCICYP2A6CHRNA7ABL1SRC | |
| SCHEMBL11955020 | 0.69 | PRKCI (0.55) | PRKCICYP2A6CHRNA7CYP19A1GRM2 | |
| SCHEMBL19119851 | 0.67 | PRKCI (0.42) | PRKCICYP2A6CHRNA7KCNH2CYP2D6 | |
| SCHEMBL1359850 | 0.66 | PTGDR2 (0.33) | PRKCI | |
| SCHEMBL16205315 | 0.65 | PRKCI (0.53) | PRKCICYP2A6CHRNA7KCNH2CYP1A2 | |
| SCHEMBL29599343 | 0.65 | PRKCI (0.53) | PRKCICYP2A6CHRNA7KCNH2CYP1A2 | |
| SCHEMBL14506379 | 0.65 | PRKCI (0.47) | PRKCICYP2A6ABL1SRCKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220332713-A1 | Monoacylglycerol Lipase Modulators | JANSSEN PHARMACEUTICA NV (BE) | 2022-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220332713-A1 | Monoacylglycerol Lipase Modulators | MGLL, LPL, PNLIP | PRKCI 1350/4885CYP2A6 747/4885CHRNA7 320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.