SCHEMBL2238415

SCHEMBL2238415

[c]1ccc2c(c1)Cc1cc3c(cc1-2)Cc1c[c]ccc1-3

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.32
MAPT P10636 2/20 0.32
RAB9A P51151 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
HPGD P15428 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4873315 0.92
SCHEMBL71211 0.91
SCHEMBL2764606 0.82 PGR (0.39) NPC1MAPTRAB9AKDM4EALDH1A1
SCHEMBL2765317 0.82 METAP1 (0.43)
SCHEMBL7802748 0.82 RAB9A (0.56) NPC1MAPTRAB9AKDM4EALDH1A1
SCHEMBL2765442 0.82 METAP1 (0.43)
SCHEMBL4824206 0.82
SCHEMBL2678990 0.82
SCHEMBL24657 0.80 MAOA (0.46) NPC1MAPTRAB9AKDM4EALDH1A1
SCHEMBL134194 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1497393-A1 ELECTROLUMINESCENT MATERIALS AND METHODS OF MANUFACTURE AND USE 3M Innovative Properties Company (US) 2005-01-19 EP claimed
US-20030224205-A1 Electroluminescent materials and methods of manufacture and use 3M INNOVATIVE PROPERTIES COMPANY 2003-12-04 US claimed
WO-2003089542-A1 ELECTROLUMINESCENT MATERIALS AND METHODS OF MANUFACTURE AND USE 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-10-30 WO claimed
US-20110309341-A1 AMINE POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME SUMATION CO., LTD. (JP) 2011-12-22 US disclosed
EP-2360201-A1 AMINE POLYMER COMPOUND AND LIGHT-EMITTING ELEMENT USING SAME Sumitomo Chemical Company, Limited (JP) 2011-08-24 EP disclosed
US-20100230666-A1 AMINE-TYPE POLYMERIC COMPOUND, AND LIGHT-EMITTING ELEMENT COMPRISING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-09-16 US disclosed
EP-2216356-A1 AMINE-TYPE POLYMERIC COMPOUND, AND LIGHT-EMITTING ELEMENT COMPRISING THE SAME Sumitomo Chemical Company, Limited (JP) 2010-08-11 EP disclosed
US-7442760-B2 Electroactive polymers 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-10-28 US disclosed
US-7442421-B2 Electroluminescent materials and methods of manufacture and use 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-10-28 US disclosed
US-20080026135-A1 ELECTRON TRANSPORT AGENTS FOR ORGANIC ELECTRONIC DEVICES 3M INNOVATIVE PROPERTIES COMPANY 2008-01-31 US disclosed
US-20070237983-A1 ELECTROLUMINESCENT MATERIALS AND METHODS OF MANUFACTURE AND USE 3M INNOVATIVE PROPERTIES COMPANY 2007-10-11 US disclosed
EP-1618169-A1 ELECTRON TRANSPORT AGENTS FOR ORGANIC ELECTRONIC DEVICES 3M Innovative Properties Company (US) 2006-01-25 EP disclosed
EP-1573789-A2 ELECTROACTIVE POLYMERS 3M Innovative Properties Company (US) 2005-09-14 EP disclosed
EP-1497393-A1 ELECTROLUMINESCENT MATERIALS AND METHODS OF MANUFACTURE AND USE 3M Innovative Properties Company (US) 2005-01-19 EP disclosed
WO-2004102615-A2 ELECTROACTIVE POLYMERS 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-11-25 WO disclosed
WO-2004096948-A1 ELECTRON TRANSPORT AGENTS FOR ORGANIC ELECTRONIC DEVICES 3M INNOVATIVE PROPERTIES COMPANY (US) 2004-11-11 WO disclosed
US-20040214036-A1 Electron transport agents for organic electronic devices 3M INNOVATIVE PROPERTIES COMPANY 2004-10-28 US disclosed
US-20040062930-A1 Electroactive polymers 3M INNOVATIVE PROPERTIES COMPANY 2004-04-01 US disclosed
US-20030224205-A1 Electroluminescent materials and methods of manufacture and use 3M INNOVATIVE PROPERTIES COMPANY 2003-12-04 US disclosed
WO-2003089542-A1 ELECTROLUMINESCENT MATERIALS AND METHODS OF MANUFACTURE AND USE 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-10-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100230666-A1 AMINE-TYPE POLYMERIC COMPOUND, AND LIGHT-EMITTING ELEMENT COMPRISING THE SAME AHR, ARNT, MLLT1 NPC1 4200/4885MAPT 2955/4885RAB9A 3591/4885
US-20110309341-A1 AMINE POLYMER COMPOUND AND LIGHT EMITTING DEVICE USING THE SAME AHR, HRH3, HRH4 NPC1 4480/4885MAPT 1067/4885RAB9A 1938/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.