Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | FASN | P49327 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | SMO | Q99835 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24658467 | 0.81 | MAOA (0.38) | MAOAFASNSMOGAAALDH1A1 | |
| SCHEMBL24658827 | 0.80 | MAOA (0.35) | MAOAFASNEPHX1SMO | |
| SCHEMBL24658658 | 0.79 | HPGD (0.34) | HPGDEPHX1KMT2AGAAALDH1A1 | |
| SCHEMBL4191188 | 0.78 | MAOA (0.47) | MAOAHPGDEPHX1KMT2ASMO | |
| SCHEMBL24658739 | 0.76 | MAOA (0.35) | MAOAFASNSMO | |
| SCHEMBL14631213 | 0.76 | ALDH1A1 (0.33) | HPGDEPHX1EPHX2ALDH1A1 | |
| SCHEMBL18361886 | 0.74 | FASN (0.39) | MAOAFASNEPHX1KMT2A | |
| SCHEMBL24973923 | 0.74 | RAB9A (0.36) | HPGDEPHX1EPHX2ALDH1A1 | |
| SCHEMBL12508713 | 0.74 | ATM (0.50) | KMT2AEPHX2ALDH1A1NPSR1 | |
| SCHEMBL18629569 | 0.73 | NPSR1 (0.56) | HPGDEPHX1KMT2AEPHX2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022173756-A1 | ANTIBACTERIAL COMPOUNDS | FORGE THERAPEUTICS, INC. (US) | 2022-08-18 | — | — | WO | disclosed |