Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.31 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13450328 | 0.82 | EPHX2 (0.45) | HPGDKMT2AEPHX1NPSR1SMN1; SMN2 | |
| SCHEMBL14631213 | 0.80 | ALDH1A1 (0.33) | HPGDEPHX1L3MBTL1ALDH1A1ATM | |
| SCHEMBL24973923 | 0.79 | RAB9A (0.36) | HPGDEPHX1SMN1; SMN2ALDH1A1 | |
| SCHEMBL24658686 | 0.79 | MAOA (0.39) | HPGDKMT2AEPHX1GAANPSR1 | |
| SCHEMBL12508713 | 0.78 | ATM (0.50) | KMT2ANPSR1SMN1; SMN2ALDH1A1ATM | |
| SCHEMBL24658472 | 0.78 | ALDH1A1 (0.33) | EPHX1NPSR1SMN1; SMN2ALDH1A1ATM | |
| SCHEMBL25106799 | 0.77 | HSD11B1 (0.40) | HPGDKMT2AEPHX1 | |
| SCHEMBL24658372 | 0.77 | KMT2A (0.57) | HPGDKMT2AEPHX1GAAL3MBTL1 | |
| SCHEMBL24658470 | 0.77 | HTR2A (0.33) | HPGDKMT2AEPHX1ATM | |
| SCHEMBL27325972 | 0.75 | TSHR (0.39) | KMT2AEPHX1NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022173756-A1 | ANTIBACTERIAL COMPOUNDS | FORGE THERAPEUTICS, INC. (US) | 2022-08-18 | — | — | WO | disclosed |