Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | ESRRB | O95718 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESRRA | P11474 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5036306 | 0.77 | MAPT (0.50) | MAPTLMNAPOLBNR4A2PGK1 | |
| SCHEMBL9724203 | 0.74 | MAPT (0.63) | MAPTLMNAPOLBNR4A2L3MBTL1 | |
| SCHEMBL5042731 | 0.72 | NCF1 (0.54) | LMNAL3MBTL1KMT2AHPGDHTT | |
| SCHEMBL31353405 | 0.71 | POLB (0.37) | MAPTLMNAPOLBNR4A2L3MBTL1 | |
| SCHEMBL9073054 | 0.71 | MAPT (0.56) | MAPTLMNAPOLBNR4A2L3MBTL1 | |
| SCHEMBL4966407 | 0.71 | LMNA (0.68) | MAPTLMNANT5EKMT2APRNP | |
| SCHEMBL4249792 | 0.71 | LMNA (0.68) | MAPTLMNAPOLBL3MBTL1ESRRB | |
| Hydrochloric Acid SCHEMBL5042755 | 0.71 | NCF1 (0.52) | LMNAL3MBTL1KMT2AHPGDHTT | |
| SCHEMBL27604183 | 0.71 | ATM (0.38) | POLBL3MBTL1HPGDCYP1A2 | |
| Hydrochloric Acid SCHEMBL27604028 | 0.70 | ATM (0.37) | POLBL3MBTL1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117279914-A | SOS1 inhibitor and preparation method and application thereof | 南京再明医药有限公司 | 2023-12-22 | — | — | CN | disclosed |
| WO-2022161461-A1 | SOS1 INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 江苏先声药业有限公司 | 2022-08-04 | — | — | WO | disclosed |
| WO-2022161461-A1 | SOS1 INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 江苏先声药业有限公司 | 2022-08-04 | — | — | WO | disclosed |