Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27604028 | 0.99 | ATM (0.37) | ATMKDM4EALDH1A1GAAHPGD | |
| SCHEMBL27604071 | 0.83 | KDM4E (0.34) | ATMKDM4EALDH1A1GAAHPGD | |
| SCHEMBL27550352 | 0.79 | ALDH1A1 (0.59) | ATMKDM4EALDH1A1GAAHPGD | |
| SCHEMBL27586210 | 0.77 | KDM4E (0.38) | ATMKDM4EALDH1A1GAAHPGD | |
| SCHEMBL27721451 | 0.76 | KDM4E (0.35) | ATMKDM4EALDH1A1GAAHPGD | |
| SCHEMBL27525080 | 0.73 | KDM4E (0.35) | ATMKDM4EALDH1A1GAAHPGD | |
| SCHEMBL27550358 | 0.72 | LMNA (0.40) | ATMKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL24658982 | 0.71 | MAPT (0.53) | HPGDCYP1A2POLBL3MBTL1 | |
| SCHEMBL27471414 | 0.70 | CCR6 (0.43) | KDM4ECYP1A2L3MBTL1 | |
| SCHEMBL27525093 | 0.70 | DGAT1 (0.43) | KDM4EGAAHPGDSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100376557-C | Quinoline derivatives as ligands for neuropeptide Y receptors | HOFFMANN LA ROCHE (CH) | 2008-03-26 | — | — | CN | disclosed |
| CN-1522249-A | Quinoline derivatives as ligands for neuropeptide Y receptors | — | 2004-08-18 | — | — | CN | disclosed |