Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PRF1 | P14222 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23363866 | 0.85 | DGAT1 (0.35) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL24847356 | 0.73 | KDM4E (0.38) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL28865246 | 0.70 | ALDH1A1 (0.44) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL26521949 | 0.69 | XDH (0.35) | MAPTMEN1KMT2ADGAT1LMNA | |
| SCHEMBL1406553 | 0.68 | ALDH1A1 (0.42) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL23363777 | 0.68 | HTR2A (0.38) | ALDH1A1DGAT1GAAHTTALOX12 | |
| Hydrochloric Acid SCHEMBL6572000 | 0.67 | ALDH1A1 (0.41) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL30363994 | 0.66 | DYRK1A (0.37) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL25063986 | 0.66 | DYRK1A (0.37) | MAPTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL26522362 | 0.66 | SLC5A2 (0.38) | NPC1RAB9AALDH1A1KDM4EDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022246459-A1 | COMBINATION THERAPY | GENENTECH, INC. (US) | 2022-11-24 | — | — | WO | disclosed |