Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | PTPRC | P08575 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29803460 | 1.00 | KMT2A (0.51) | KMT2ALMNARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL24669370 | 0.86 | LMNA (0.55) | KMT2ALMNARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29803423 | 0.86 | LMNA (0.55) | KMT2ALMNARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL24670924 | 0.85 | RAB9A (0.69) | KMT2ALMNARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL24669477 | 0.81 | RAB9A (0.53) | KMT2ALMNARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL29803393 | 0.80 | MAPT (0.72) | KMT2ALMNARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL24671304 | 0.80 | MAPT (0.72) | KMT2ALMNARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL24670991 | 0.79 | RAB9A (0.56) | KMT2ALMNARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL24460162 | 0.78 | TMPRSS4 (0.64) | KMT2ALMNARAB9ASMN1; SMN2NPC1 | |
| SCHEMBL24670710 | 0.76 | MAPT (0.75) | KMT2ALMNARAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |